In clinical trials, a combination of vitamin D3 and vitamin K2 (especially the vitamin K subtype MK-7) increased bone density in postmenopausal women with osteoporosis more effectively than each vitamin taken individually or a placebo.īesides bone health, the interaction between vitamins D and K in relation to cardiovascular health has been receiving growing research interest. Vitamin D3 works together with vitamin K2 in maintaining calcium balance in the body, affecting the activation of the bone protein (osteocalcin) responsible for the incorporation of calcium in the bones. It also helps in regulating the calcium-phosphorus ratio required for healthy bones. It is well known that vitamin D is needed for the effective absorption of calcium from the digestive system, and promoting its mobilization towards the bones.
The two different types of vitamin D are D2 (ergocalciferol), present in plant-based products such as mushrooms, and D3 (cholecalciferol), present in animal products and fatty fish. Vitamin D by itself is important for maintaining strong bones and a healthy cardiovascular and immune system. While these two fat-soluble vitamins have many health benefits, they work best when combined. In previous articles we discussed the benefits of vitamin D and vitamin K when used individually.
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